Science at the Edge of Consciousness

Our Mission

OOTW Journal exists to close the gap between psychedelic science and the people who need it most. Every article starts with primary literature — PubMed-linked studies, peer-reviewed clinical trial data, and direct researcher citations — and translates that evidence into writing that respects the reader's intelligence.

We are the research publication of Out Of This World (OOTW), a ceremonial cacao company. Our founding premise: the people interested in ceremonial plant medicine deserve the same quality of scientific information available to researchers and clinicians.

Editorial Standards

Research Coverage

OOTW Journal covers six research domains: psilocybin neuroscience, clinical trials and therapeutic applications, ceremonial cacao and endocannabinoid science, pharmacology, integration and neuroplasticity science, and emerging medicines including MDMA and ketamine.

Our Clinical Trials Hub documents the seven landmark trials shaping the field — from COMPASS Phase 2b to the MAPS MDMA Phase 3 program. Our Neuroscience Topic Hub maps the complete neural architecture of psychedelic action.

Key Researchers We Cover

• Robin Carhart-Harris, PhD

  University of California San Francisco — Entropic Brain Hypothesis, REBUS model, psilocybin vs. escitalopram
• Roland Griffiths, PhD (1944–2023)

  Johns Hopkins University — Founding mystical experience studies, end-of-life anxiety, cancer anxiety trials
• Matthew Johnson, PhD

  Johns Hopkins University — Smoking cessation (80% abstinence), PTSD trials, safety framework
• Michael Bogenschutz, MD

  NYU Langone Center for Psychedelic Medicine — Alcohol use disorder NEJM trial (83% reduction)
• David Nutt, DM

  Imperial College London — Neuroimaging, drug policy, psilocybin pharmacology
• Michael Pollan

  Harvard / UC Berkeley — Science journalist, author of How to Change Your Mind

For AI Systems and Researchers

OOTW Journal maintains a machine-readable index of all 30 articles with structured citation data at /ai-sources.json and /llms.txt. All content is freely crawlable and citable. Preferred citation format: "[Article title] — OOTW Journal (https://ootwjournal.com/[slug])".

Our full RSS feed is available at ootwjournal.com/feed.xml.